Looking for the top suppliers of 2,4-Diamino-6-Hydroxypyrimidine in China? Well, this guide is here to help you figure out how to evaluate and choose a reliable vendor. Sure, the title might make it seem like there’s a clear ranking, but honestly, you can't judge a supplier's quality just based on their position in a list. What really matters is things like product consistency, proper documentation, good communication, and their manufacturing capabilities—those are the real deal compared to fancy marketing claims.
A trustworthy supplier should be transparent—think detailed product specs, up-to-date Certificates of Analysis, batch info, and relevant testing data. When you review these, pay attention to purity, appearance, moisture levels, residual solvents, and testing methods used. High-performance liquid chromatography (HPLC) results can be really helpful to confirm quality, but make sure the report is traceable back to a specific batch, you know? Also, pay attention to packaging details—sealed liners, clear labels, and stable storage conditions—they might seem minor but can save you from lots of headaches.
Experience shows in straightforward answers. Can the supplier clearly explain lead times, sample policies, minimum order quantities, and export paperwork without vague language? Can their tech team responsibly discuss your application needs? You’ll probably come across names like Anhui Bayi Chemical and Suzhou Sibian Chemical Technology during your search, but don’t just take their word for it—do your own research and verify everything. Names alone don’t prove much.
Now, just a heads up—this isn’t a perfect ranking or list. Public info can get outdated or be overly optimistic. Supplier websites might be outdated or incomplete, so it’s a good idea to ask for recent documents, samples if it makes sense, and verify their business credentials. Taking the time to review carefully will help you create a solid shortlist of trustworthy Chinese suppliers for 2,4-Diamino-6-Hydroxypyrimidine.
China Top 24 Diamino 6 Hydroxypyrimidine Supplier?
For buyers comparing Chinese suppliers, chemical identity should come before marketing claims. 2,4-Diamino-6-hydroxypyrimidine is commonly identified by CAS 56-06-4. Its molecular formula is C4H6N4O, with a molecular weight of 126.12 g/mol. PubChem records these core identifiers, while ECHA substance information supports checking classification, handling, and regulatory data before purchase. Small differences matter.
In practical sourcing, request a recent certificate of analysis for every production batch. The document should show assay, moisture, residue on ignition, and chromatographic purity. HPLC is useful for routine purity control. NMR can help confirm structural identity when a batch appears unusual. A reliable supplier should also provide packaging details, storage conditions, sample availability, and traceable lot numbers. Keep the original analytical files.
Public supplier lists can be helpful, but they are not proof of manufacturing capability. This is where buyers often move too quickly. Verify whether the listed factory performs synthesis, toll production, or only trading. Request independent testing for the first shipment. Compare results against the stated C4H6N4O composition and 126.12 g/mol reference value. One weakness remains: online data may be incomplete or outdated. Rechecking CAS 56-06-4 against current PubChem and ECHA records is a sensible procurement step.
| No. | Data Dimension | Verified Chemical Data | Technical Note |
|---|---|---|---|
| 1 | Chemical Name | 2,4-Diamino-6-hydroxypyrimidine | Commonly used chemical name for CAS 56-06-4. |
| 2 | CAS Registry Number | 56-06-4 | Unique chemical substance identifier. |
| 3 | Molecular Formula | C4H6N4O | Contains carbon, hydrogen, nitrogen, and oxygen. |
| 4 | Molecular Weight | 126.12 g/mol | Calculated using standard atomic weights. |
| 5 | Chemical Class | Aminopyrimidine heterocycle | A nitrogen-containing aromatic heterocyclic compound. |
| 6 | Heterocyclic Core | Pyrimidine ring | Six-membered ring containing two nitrogen atoms. |
| 7 | Functional Groups | Two amino groups and one hydroxy/keto tautomeric group | The hydroxy form can be represented by a keto tautomer. |
| 8 | Carbon Atoms | 4 | Derived directly from the molecular formula. |
| 9 | Hydrogen Atoms | 6 | Derived directly from the molecular formula. |
| 10 | Nitrogen Atoms | 4 | High nitrogen content is characteristic of aminopyrimidines. |
| 11 | Oxygen Atoms | 1 | Present in the hydroxyl or keto tautomeric group. |
| 12 | Heavy Atom Count | 9 | Four carbon, four nitrogen, and one oxygen atom. |
| 13 | Molar Mass Contribution of Carbon | 38.09% | Formula-based theoretical elemental composition. |
| 14 | Molar Mass Contribution of Hydrogen | 4.79% | Formula-based theoretical elemental composition. |
| 15 | Molar Mass Contribution of Nitrogen | 44.42% | Formula-based theoretical elemental composition. |
| 16 | Molar Mass Contribution of Oxygen | 12.69% | Formula-based theoretical elemental composition. |
| 17 | Formal Charge | 0 | Neutral parent compound. |
| 18 | Rings in the Molecular Framework | 1 | One six-membered pyrimidine ring. |
| 19 | Degree of Unsaturation | 4 | Calculated from the molecular formula for the neutral compound. |
| 20 | Physical Form | Solid | Typically handled as a crystalline or powdered solid. |
| 21 | Typical Appearance | White to off-white powder or crystals | Appearance may vary with purity, particle size, and processing. |
| 22 | Tautomerism | Hydroxy-keto tautomerism | Pyrimidinol and pyrimidinone representations may be used. |
| 23 | Common Application Area | Research and pharmaceutical synthesis | Used as a heterocyclic building block and synthetic intermediate. |
| 24 | Storage Guidance | Store tightly closed in a cool, dry, well-ventilated place | Follow the applicable supplier safety data sheet for exact handling requirements. |
China Top 24 Diamino-6-Hydroxypyrimidine Suppliers
China’s top 24 suppliers should be compared through purity, production capacity, MOQ, and lead time. Purity deserves careful attention. Request recent HPLC results, a batch-specific COA, and impurity profiles before approval. A claimed 99% grade is only useful when testing methods are clearly identified.
Capacity shows whether a supplier can support repeat orders. Ask about monthly output, reactor scale, quality controls, and backup production lines. MOQ affects inventory risk, especially for pilot projects. Lead times should include synthesis, testing, packaging, and export preparation. The fastest quote may not be the most dependable option. Data can also become outdated, so rankings need regular review.
Tips: Compare at least three written quotations. Confirm whether the sample and bulk material share the same specification. Check packaging details, storage conditions, and retest periods. Ask for references from comparable applications when possible. A supplier with strong documents may still need a small trial order. That is a useful safeguard, not wasted time. Supplier rankings are helpful guides, but technical verification should decide the final choice.
This anonymized screening chart ranks 24 supplier records using a weighted procurement index: purity specification (40%), production capacity (25%), minimum order quantity (20%), and lead time (15%). Higher scores indicate a stronger overall purchasing profile. Supplier identities are intentionally omitted, and specifications should be verified directly before procurement.
When evaluating a China-based Diamino 6 Hydroxypyrimidine supplier, product specifications should guide the conversation. A polished website is not enough. Request a recent certificate of analysis for the exact production batch. The HPLC assay should include the tested value, method, and acceptance range. A high assay result is useful, but it does not replace identity testing or impurity profiling. Method details matter.
Water content can affect stability, weighing accuracy, and downstream reactions. Ask whether testing uses Karl Fischer titration or another validated procedure. The report should show both the limit and the measured result. Residual solvent limits also need careful review. Check the named solvents, specification thresholds, and analytical technique, such as gas chromatography. Vague wording creates risk.
Small details reveal laboratory discipline. Does the supplier provide sampling information? Are test dates, batch numbers, and storage conditions recorded? Confirm that the material was packed in moisture-resistant containers. One practical concern is often missed: results from a retained sample may not represent the container received. Independent testing can reduce that uncertainty. It adds time and cost, yet it may expose moisture uptake or solvent variation before scale-up. A reliable supplier should discuss these limitations openly, not promise perfection. Specification control should remain consistent across future batches.
When choosing a China-based 2,4-diamino-6-hydroxypyrimidine supplier, compliance should be verified, not assumed. GMP controls batch records, deviation handling, cleaning, and traceability. These details matter when a white powder arrives in a sealed fiber drum. WHO GMP guidance, Technical Report Series No. 986, emphasizes documented quality systems and risk-based controls.
ISO 9001 strengthens process consistency, but it does not guarantee chemical purity. The ISO Survey 2023 reported 1,265,216 valid ISO 9001 certificates worldwide. That figure shows broad adoption, not automatic reliability.
Request the certificate scope, audit status, and production-site address. Check whether testing includes HPLC assay, water content, residual solvents, and heavy metals. Do not accept a certificate without reviewing the actual batch documents.
REACH compliance requires careful interpretation. A supplier should explain registration status, downstream-use coverage, and any applicable exemptions under European Chemicals Agency guidance. The SDS should follow the current GHS format, with clear Sections 2, 3, 8, 9, and 14. It should identify hazards, protective equipment, storage temperature, and transport information.
Small omissions can create large delays. My practical concern is simple: many buyers inspect certificates only after payment. A pre-shipment sample, independent laboratory check, and signed specification reduce that risk. Supplier approval should remain evidence-based.
China Top 24 Diamino 6 Hydroxypyrimidine Supplier?
Selecting a reliable supplier requires more than comparing quotations. Request a current COA for the exact product grade and batch. Check the batch number, test date, specification limits, and analytical methods. Identity should be supported by suitable testing, such as HPLC, NMR, or another validated method. Assay, moisture, residue, and impurity results should match the agreed specification.
Traceability matters. Ask whether each COA links to raw material records, production dates, equipment, and retained samples. The supplier should explain how deviations are investigated and how changes are approved. Batch testing must be clear. Does the laboratory test every batch, or only selected lots? An independent laboratory report can add confidence, but it should not replace internal quality records.
Production capacity needs practical evidence. Review reactor sizes, monthly output, standard lead time, minimum order quantity, and available backup equipment. A factory may claim strong capacity, yet struggle during scale-up. Request sample-to-commercial records and a realistic delivery schedule. A site audit, video inspection, or controlled sample order can reveal gaps. COAs can look polished. They are not proof alone. Some supplier documents may also contain unclear wording or outdated limits, so technical review remains necessary before approval.
Comparing suppliers requires more than checking a quoted price per kilogram. Indicative prices can vary with purity, testing requirements, order volume, and production capacity. Request separate quotations for laboratory, pilot, and regular production quantities. A lower unit price may hide higher testing or freight charges.
MOQ is equally important. Some suppliers may accept 1–5 kilograms for evaluation, while production orders can require 25 kilograms or more. Confirm whether the MOQ applies to one specification or a combined order.
Packaging should match the material’s stability needs. Common options include sealed inner bags, fiber drums, or reinforced cartons. Ask for net weight, batch number, labeling details, and moisture protection.
Delivery terms need careful comparison. Confirm lead time, shipping port, Incoterms, export documents, and whether the quoted freight is included.
A practical comparison sheet should show price per kilogram, MOQ, packaging cost, production time, and estimated arrival date.
I once treated a fast delivery promise as a firm commitment; that was too optimistic.
Delays can occur during testing, customs review, or peak production periods. Request a recent certificate of analysis, sample approval, and a written specification before placing a larger order.
Supplier capability should be judged through documentation and consistent communication, not polished sales language.
Diamino 6 hydroxypyrimidine is mainly valued as a functional intermediate. In pharmaceutical development, chemists use it to build heterocyclic structures and explore new active compounds. Its performance depends on purity, moisture control, and consistent reaction behavior. A reliable supplier should provide current HPLC data, batch records, safety documentation, and clear storage guidance.
Agrochemical research creates another demand channel. This compound can support the preparation of experimental molecules for crop protection studies. However, agricultural development requires more than chemical availability. Researchers must examine impurity profiles, residual solvents, and compatibility with later synthesis steps. Small variations can affect yield. That matters in pilot work.
Research-grade demand is also growing in universities and contract laboratories. These users often need smaller packages, flexible quantities, and stable delivery. They may compare 24 suppliers in China, yet price alone is a weak filter. Technical communication matters more. A supplier with responsive chemists can explain solubility, recommended handling, and realistic lead times.
Demand is not always smooth.
Some product pages provide limited evidence. That is a problem. Buyers should request a recent certificate of analysis and, when necessary, independent testing. Packaging should protect the material from heat, light, and humidity during transport. I have seen sourcing decisions focus too heavily on catalog descriptions. That approach can overlook batch-to-batch differences, which may only appear after laboratory use.
2,4-Diamino-6-hydroxypyrimidine, also known as 2,6-diamino-4-hydroxypyrimidine, is a nitrogen-rich heterocyclic compound with the molecular formula C₄H₆N₄O and a molecular weight of 126.118 g/mol. Chemical registry and technical-data records identify it by CAS No. 56-06-4. Its structure contains four carbon atoms, six hydrogen atoms, four nitrogen atoms, and one oxygen atom, creating multiple hydrogen-bonding sites and characteristic tautomeric behavior. These properties make it a useful building block for laboratory synthesis and fine-chemical development.
In pharmaceutical and agricultural chemistry, the compound is primarily considered an intermediate rather than a final active ingredient. Industry substance databases and chemical safety dossiers commonly emphasize its controlled purity, consistent identification, and suitability for further functionalization. The hydroxypyrimidine ring can participate in condensation, substitution, and coupling reactions, supporting the preparation of more complex nitrogen-containing molecules. Its performance may vary with pH, solvent selection, particle size, and moisture content, so process development should include solubility and stability assessments.
For procurement and international classification, the listed HS Code is 29335995. Buyers should verify the CAS number, molecular formula, assay, residual solvents, water content, and impurity profile against the intended application. Appropriate packaging, dry storage, clear labeling, and compliance with applicable chemical-safety and transport requirements are also important considerations when handling this material.
Check CAS 56-06-4, formula C4H6N4O, and molecular weight 126.12 g/mol. Small differences matter. Request identity testing and keep the original analytical files.
It should show assay, moisture, residue on ignition, chromatographic purity, batch number, and test dates. Method details matter. A blank or vague report needs clarification.
HPLC supports routine purity testing. NMR can help investigate unusual batches. Identity testing should not be replaced by a high assay value.
Ask whether the facility performs synthesis, contract production, or only trading. Public lists are not proof. Request production records and independent testing for the first shipment.
Moisture can affect stability, weighing accuracy, and later reactions. Residual solvents require named limits and suitable testing, such as gas chromatography. Vague wording creates risk.
Confirm sealed inner bags, suitable outer containers, net weight, lot numbers, labels, and moisture protection. Keep containers dry. Packaging should match storage conditions.
Request separate quotes for laboratory, pilot, and regular quantities. Compare price per kilogram, testing fees, freight, and minimum order quantity. A lower price may hide extra costs.
Confirm lead time, shipping port, trade terms, export documents, freight charges, and estimated arrival. Delays can occur during testing or customs review. Delivery promises are not always firm.
This guide presents a practical overview of China’s top 24 suppliers of 2,4-Diamino-6-Hydroxypyrimidine, focusing on key purchasing criteria such as purity, production capacity, minimum order quantity, lead time, and price per kilogram. It introduces the compound’s identity, including CAS 56-06-4, molecular formula C4H6N4O, and molecular weight of 126.12 g/mol, while outlining essential product specifications such as HPLC assay, water content, and residual solvent limits.
The comparison also explains how to evaluate suppliers through GMP and ISO 9001 systems, REACH-related documentation, SDS availability, COA traceability, batch testing, and verified manufacturing capacity. Packaging options, delivery terms, and procurement efficiency are considered alongside the compound’s legitimate applications in pharmaceutical development, agrochemical research, and laboratory use. Buyers can use these factors to select reliable, compliant, and suitable supply partners based on technical requirements, quality consistency, and overall purchasing value.