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Shijiazhuang Pengnuo Technology Releases A Series of Pyrimidine Pharmaceutical Intermediates to Empower Global Pharmaceutical Supply Chain

Shijiazhuang Pengnuo Technology keeps expanding its portfolio of fine chemicals. We are pleased to launch three high-value pyrimidine heterocyclic intermediates:

6-Amino-1,3-dimethyluracil (CAS:6642-31-5), 4-Chloro-2,6-diaminopyrimidine (CAS:156-83-2), 2,4-Diamino-6-hydroxypyrimidine (CAS:56-06-4).

As fundamental building blocks for pharmaceutical synthesis, these products feature stable supply and consistent quality, now available for pharmaceutical manufacturers and research institutes worldwide.

Product Introduction

1. 6-Amino-1,3-dimethyluracil | CAS: 6642-31-5

A vital uracil derivative widely used as a key intermediate for Caffeine, Nifekalant, Urapidil and other cardiovascular medicines. It also serves as a scaffold for R&D of antiviral and anti-tumor candidates.

Thanks to stable molecular structure and moderate reactivity, it fits both lab-scale research and commercial production. Pengnuo supplies high-purity grades with excellent batch-to-batch uniformity.

2. 4-Chloro-2,6-diaminopyrimidine | CAS: 156-83-2

The core intermediate for Minoxidil synthesis. It is also applied in manufacturing antihypertensive drugs, kinase inhibitors and antibacterial agents.

The active chlorine group enables convenient nucleophilic substitution, making it irreplaceable in pyrimidine drug synthesis. Off-white crystalline powder with strictly controlled impurities, meeting quality standards for API and cosmetic raw material production.

3. 2,4-Diamino-6-hydroxypyrimidine | CAS: 56-06-4

A fundamental upstream building block, which can be chlorinated to produce 4-Chloro-2,6-diaminopyrimidine. It is widely adopted in the synthesis of folate anti-cancer drugs, diuretics and antimalarial compounds.

It acts as the starting material for pterin and purine derivatives, enjoying growing demand in new drug discovery. Stable for storage, serving as a foundational raw material linking upstream and downstream pyrimidine production.

The three items form a matched product chain: 2,4-Diamino-6-hydroxypyrimidine can be converted into 4-Chloro-2,6-diaminopyrimidine via chlorination. Global buyers can source all related materials in one stop to simplify procurement management.

About Shijiazhuang Pengnuo Technology

Pengnuo Technology specializes in fine chemicals and pharmaceutical intermediate export, serving clients across Europe, Southeast Asia, India, the Middle East and other regions.

We implement strict quality control throughout raw material selection, production and final testing. We provide COA documents, customized packaging, flexible MOQ, covering lab sample orders and bulk commercial shipments. Supported by convenient logistics in Hebei Province, we arrange sea and land transportation efficiently to guarantee on-time delivery.

Moving forward, Pengnuo will continuously develop more pyrimidine and heterocyclic fine chemicals. We aim to be your trusted Chinese supplier with reliable supply, competitive pricing and professional technical support.
www.pengnuochemical.com

Shijiazhuang Pengnuo Technology Co., Ltd.


Post time: Aug-17-2026